To make room for Mark Teixeira and Kevin Youkilis on the 25-man roster, the Yankees have optioned pitchers Ivan Nova and Vidal Nuno to Triple-A.
Niese was examined Thursday and diagnosed with shoulder tendinitis. While the left-hander is 3-5 with a 4.40 ERA in 11 starts, Niese allowed one run in seven innings against the Yankees on Monday.
The Mets have taken three in a row from their crosstown rivals for their first four-game winning streak of the year and will go for a Big Apple whitewash in the finale Thursday night at Yankee Stadium.
Nate McLouth homered leading off the bottom of the 10th inning, Chris Dickerson hit a pair of solo shots and the Baltimore Orioles beat the New York Yankees 3-2 Tuesday night to snap a six-game losing streak.
New York placed left-handed pitcher Andy Pettitte on the DL with a strained left trapezius on Friday evening ahead of the Yankees’ series-opening game against the Blue Jays at Yankee Stadium.
Granderson was activated on Tuesday by the Yankees, and in the lineup against Seattle batting fourth and playing left field. New York optioned left-hander Vidal Nuno to Triple-A Scranton/Wilkes-Barre.
Vidal Nuno pitched five innings of three-hit ball to win his first major league start, Vernon Wells and Lyle Overbay had two RBIs apiece and the New York Yankees beat the Cleveland Indians, 7-0, on Monday for a doubleheader split.
The Yankees will have to make due without starter Ivan Nova and catcher Francisco Cervelli who both land on the DL.