The crash occurred shortly before 6 a.m. on Route 3 where it meets Interstate 495 in North Bergen, on the way to the Lincoln Tunnel.
Icy conditions prompted police to shut down a stretch of the Long Island Expressway in Suffolk County Tuesday evening.
The early Saturday morning crash left three people dead and two others injured. The second survivor remains hospitalized in critical condition but is expected to survive.
A nasty crash in Hudson County, N.J. left two people dead and three others in critical condition early Saturday.
The Lincoln Tunnel was back open Wednesday night, but delays persisted hours after the outbound tunnel was closed due to a truck debris spill.