Gregory Brandel, 35, was driving westbound on Fulton Street around 11:30 p.m. when he collided with a car driven by 58-year-old Patricia Fuzia, police said.
Fuzia was turning onto Fulton Street from Nelson Street when the collision occurred.
Police said Fuzia was pronounced dead at the scene.
Brandel was rushed to a local hospital where he later died.
The investigation is ongoing.